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In the latest analyze, we noted the identification as well as the characterization of a fresh atypical opioid receptor with unique damaging regulatory properties towards opioid peptides.1 Our final results confirmed that ACKR3/CXCR7, hitherto often known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is also a broad-spectrum sc